Very much so, especially since there's history on one side of my family. I can only hope it's not hereditary. If it were just meds, I wouldn't be concerned all that much myself. I don't think these change physiology long-term, but mainly just correct imbalances as needed (but then I'm no doctor).
If a downward spiral starts, I hope we have enough self-awareness and faculties left to notice and do something about it. On the other hand, gliding obliviously to the bottom need not necessarily be bad, provided no one else gets hurt in the process.
Along those lines, I've got a bunch of (maybe silly) tests to check if it's happening, such as multiplying small numbers in my head, standing on one foot while tying a shoe, reciting old lyrics or poems I've known by heart, etc. I guess these are sort of like the dementia test Trump bragged about acing. Maybe I'll add that particular test to my list, since it's online.